RNA Details
Disease Name
cardiomegaly
Tissue
heart
RNA Symbol
IGF-IIR
RNA ID
RNA Type
mRNA
Alteration Pattern
histone acetylation
Species
homo sapiens
Detection Methods
NA
Target
NA
Pathway
NA
PubMed ID
Title
Histone acetylation is essential for ANG-II-induced IGF-IIR gene expression in H9c2 cardiomyoblast cells and pathologically hypertensive rat heart.
Year
2013
Function
Histone acetylation plays a critical role in IGF-iir up-regulation during pathological cardiac diseases and might provide a targeting gene in transcriptional therapies for the failing heart.